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Friday, 12 February 2016 ▲
Novel tea tree oil nanoemulsions for inhalation therapies of bacterial and fungal pneumonia


Instead of using antibacterial agents to treat pneumonia, a novel nano-formulation of tea tree oil (nanoTTOs) can be administered to patients. The nanoTTOs has shown high anti-Candida albicans effect than antibiotics such as fluconazole, which is usually administered to patients with pneumonia.  The inhaled nanoTTOs would be an ideal medicine for the therapy of fungal or bacterial pneumonia.

As we understand, the clinically available range of antifungal agents is small and drug resistant strains are rising. Thus, an alternative antifungal agent, nanoTTOs, is a preferred therapy of fungal pneumonia. Azole antifungal agents prevent the synthesis of ergosterol, a major component of fungal plasma membranes. 

References: 

  • Miao, L, Zhua, L, Liua, b, Dua, L, Jiac, X, Hanc, L (2016). Tea tree oil nanoemulsions for inhalation therapies of bacterial and fungal pneumonia. Sciencedirect. Retrieved 12th Feb 2016, from <http://www.sciencedirect.com/science/article/pii/S0927776516300972>



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